DOH reiterates warning vs ‘gluta’ drip as skin whitener

MANILA, Philippines — The Department of Health (DOH) has reiterated its warning against using glutathione for skin lightening after photos of actress Mariel Rodriguez-Padilla receiving a “gluta drip” in the Senate circulated online.

Glutathione drips, particularly those marketed for skin whitening and rejuvenation, have seen a rise in popularity in the Philippines.

“The DOH does not support the use of glutathione for skin whitening,” the agency said in a statement Saturday evening.

Citing an advisory issued by the country’s Food and Drug Administration (FDA) in 2019, the DOH said it “categorically states that there are no published clinical trials that have evaluated the use of injectable glutathione for skin lightening.”

The department added that there are no published guidelines for appropriate dosing regimens and duration of treatment. 

The FDA has not approved any injectable products for skin whitening. Injectable glutathione is only permitted as an adjunct treatment in cisplatin chemotherapy. 

According to the FDA, injectable glutathione for skin lightening carries risks of toxic effects on the liver, kidneys, and nervous system, along with the possibility of Steven Johnson Syndrome. 

Concerns were also raised about possible long-term skin cancer risks associated with glutathione use.

Last month, a 39-year-old woman died just hours after getting intravenous (IV) glutathione and stem cell treatments at a clinic in Quezon City. 

The victim’s death certificate stated the immediate cause of her death as anaphylactic shock—or a severe, life-threatening allergic reaction. Glutathione and stem cell intravenous infusion was identified as the antecedent cause.

Following the incident, Health chief Teodoro Herbosa noted that “it’s off-label use and illegal.”

The DOH advised those who experience side effects from glutathione to seek medical action immediately and report to the FDA at [email protected] or through the agency’s website. They may also call the Center for Drug Regulation and Research at (02) 8809-5596.

“For the next steps to take should you think that injectable glutathione was wrongly prescribed for you by a physician, please consult a practicing lawyer or